Publications

January 2024

  • Superhydrophobic polyether sulfone (PES) dialysis membrane with enhanced hemocompatibility and reduced human serum protein interactions: Ex vivo, in situ synchrotron imaging, experimental, and computational studies
    Denis Kalugin, Jumanah Bahig, Ahmed Shoker, Huu Doan, Shelley Kirychuk & Amira Abdelrasoul
    DOI: 10.1016/j.seppur.2023.126071

  • Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition
    Min-Chun Liao, Chao-Sheng Lo, Yu-Chao Pang, Wen-Xia Yang, Ke Su, Xin-Ping Zhao, Kana N. Miyata, Junzheng Peng, Julie R. Ingelfinger, John S.D. Chan & Shao-Ling Zhang.
    DOI: 10.1016/j.trsl.2024.01.002

December 2023

  • Sex-dependent effects of Canagliflozin on kidney protection in mice with combined hypertension-type 1 diabetes
    Mayra Trentin-Sonoda, Véronique Cheff , Alex Gutsol & Richard L. Hébert
    DOI: 10.1371/journal.pone.0295284

  • Uremic metabolite-zwitterionic hemocompatible poly ether sulfone dialysis membranes: Computational and hemocompatibility assessment based on hydration layer stability and ex-vivo investigations
    Arash Mollahosseini, Jumanah Bahig, Ahmad Shoker & Amira Abdelrasoul
    DOI: 10.1016/j.surfin.2023.103536

November 2023

  • In situ synchrotron quantitative analysis of competitive adsorption tendency of human serum protein to different clinical hemodialysis membranes and assessment of potential impacts
    Amira Abdelrasoul, Heloisa Westphalen, Denis Kalugin, Huu Doan & Ahmed Shoker
    DOI: 10.1016/j.bea.2023.100104

  • The extrafollicular B cell response is a hallmark of childhood idiopathic nephrotic syndrome
    Tho-Alfakar Al-Aubodah, Lamine Aoudjit, Giuseppe Pascale, Maneka A. Perinpanayagam & David Langlais
    DOI: 10.1038/s41467-023-43504-8

October 2023

  • Both sexes develop DKD in the CD1 uninephrectomized streptozotocin mouse model
    Jackie Trink, Ifeanyi Kennedy Nmecha, Dan Zhang, Melissa MacDonald, Bo Gao, & Joan C Krepinsky
    DOI: 10.1038/s41598-023-42670-5

  • Enhancing the hemocompatibility of polyethersulfone (PES) hemodialysis membranes using synthesized pseudo zwittronic polymers with various orientations
    Anubhab Patra, Jumanah Bahig, Denis Kalugin, Arash Mollahosseini, Ahmed Shoker & Amira Abdelrasoul
    DOI: 10.1016/j.rsurfi.2023.100159

  • GWAS for the composite traits of hematuria and albuminuria
    Sarah A. Gagliano Taliun, Ian R. Dinsmore, Tooraj Mirshahi, Alexander R. Chang, Andrew D. Paterson & Moumita Barua
    DOI: 10.1038/s41598-023-45102-6

  • Urinary Tract Infections: Renal Intercalated Cells Protect against Pathogens
    Forough Chelangarimiyandoab, Priyanka Mungara, Manav Batta & Emmanuelle Cordat
    DOI: 10.1681/ASN.0000000000000187

September 2023

  • A novel multi-ancestry proteome-wide Mendelian randomization study implicates extracellular proteins, tubular cells, and fibroblasts in estimated glomerular filtration rate regulation
    Matthew B. Lanktree, Nicolas Perrot, Andrew Smyth, Michael Chong, Sukrit Narula, Meera Shanmuganathan, Zachary Kroezen, Philip Britz-Mckibbin, Mario Berger, Joan C. Krepinsky, Marie Pigeyre, Salim Yusuf & Guillaume Paré.
    DOI: 10.1016/j.kint.2023.08.025

  • Hedgehog signalling in Foxd1+ embryonic kidney stromal progenitors controls nephron formation via Cxcl12 and Wnt5a
    Robert D’Cruz, Yun-Kyo Kim, Jaap Mulder, Neke Ibeh, Nan Jiang, Yilin Tian & Norman D Rosenblum
    DOI: 10.1002/path.6195

August 2023

  • Heparin-Immobilized Polyethersulfone for Hemocompatibility Enhancement of Dialysis Membrane: In Situ Synchrotron Imaging, Experimental, and Ex Vivo Studies
    Denis Kalugin, Jumanah Bahig, Ahmed Shoker & Amira Abdelrasoul
    DOI: 10.3390/membranes13080718

June 2023

  • Tungsten toxicity on kidney tubular epithelial cells induces renal inflammation and M1-macrophage polarization
    Jonatan Barrera-Chimal, Nathalie Henley, Michael Philip Grant, Schrodinger Cenatus, Pedro Geraldes, Vincent Pichette & Casimiro Gerarduzzi
    DOI: 10.1007/s10565-023-09817-6

May 2023

  • In-situ synchrotron imaging, experimental, and computational investigations on the efficiency of Trametes versicolor laccase on detoxification of P-Cresyl Sulfate (PCS) Protein Bound Uremic Toxin (PBUT)
    Shaghayegh Sadaati, Sana Daneshamouz, Jumanah Bahig, Ahmed Shoker & Amira Abdelrasoul
    DOI: 10.1016/j.jbiotec.2023.03.011

April 2023

  • Hedgehog-GLI mediated control of renal formation and malformation
    Dina Greenberg, Robert D’Cruz, Jon L. Lacanlale, Christopher J. Rowan & Norman D. Rosenblum
    DOI: 10.3389/fneph.2023.1176347

  • Hypertension in pediatric kidney transplantation
    Tomáš Seeman, Robert L. Myette & Janusz Feber
    DOI: 10.1111/petr.14522

  • Urinary podocyte-derived large extracellular vesicles are increased in paediatric idiopathic nephrotic syndrome
    Robert L Myette, Fengxia Xiao, Pavel Geier, Janusz Feber, Dylan Burger, Christopher R J Kennedy
    DOI: 10.1093/ndt/gfad086

March 2023

  • Alport Syndrome: Clinical Spectrum and Therapeutic Advances
    Vanessa De Gregorio, Emine Bilge Caparali, Azadeh Shojaei, Samantha Ricardo & Moumita Barua
    DOI: 10.1016/j.xkme.2023.100631

  • Analysis of gene expression and use of connectivity mapping to identify drugs for treatment of human glomerulopathies
    Chen-Fang Chung, Joan Papillon, José R. Navarro-Betancourt, Julie Guillemette, Ameya Bhope, Amin Emad & Andrey V. Cybulsky
    DOI: 10.3389/fmed.2023.1122328

February 2023

  • Cell surface GRP78 regulates TGFβ1-mediated profibrotic responses via TSP1 in diabetic kidney disease
    Jackie Trink, Usman Ahmed , Kian O’Neil, Renzhong Li, Bo Gao &Joan C Krepinsky
    DOI: 10.3389/fphar.2023.1098321

  • High fat diet is protective against kidney injury in hypertensive-diabetic mice, but leads to liver injury
    Véronique Cheff, Mayra Trentin-Sonoda, Amélie Blais, Jean-François Thibodeau, Chet E. Holterman, Alex Gutsol, Christopher R. J. Kennedy & Richard L. Hébert
    DOI: 10.1371/journal.pone.0281123

January 2023

  • A therapeutic target for CKD: activin A facilitates TGFβ1 profibrotic signaling
    Asfia Soomro,  Mohammad Khajehei, Renzhong Li, Kian O’Neil , Dan Zhang, Bo Gao , Melissa MacDonald, Masao Kakoki & Joan C Krepinsky.
    DOI: 10.1186/s11658-023-00424-1

  • In-situ synchrotron quantitative analysis of competitive adsorption tendency of human serum proteins on polyether sulfone clinical hemodialysis membrane
    Amira Abdelrasoul, Ning Zhu, Huu Doan & Ahmed Shoker 
    DOI: 10.1038/s41598-023-27596-2